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Barbara Spagnolo graduated summa cum laude in Neurobiology, at University of Torino , by disserting a thesis on “Analysis of motor nervous systems and motor performance of APPPS1 mice, model for Alzheimer Disease”. Working on this subject she was involved in electrophysiological, behavioral and immunohistochemical experiments and data analysis. This included animal handling during in vivo experiments to analyze motor skills, neurosurgery (cerebellar peduncle lesions), single and multiunit electrophysiology and mouse perfusion/fixation. After a PhD in Biomolecular Nanotechnologies  focused on the application of 3D micro and nanofabrication approaches applied to life science (cancer), she worked on the development of transgenic cell lines for optogenetics. In the last four years she also developed different optrode designs for simultaneous optical control and electrophysiological readout of neural activity and tested them in vivo. In 2021 she started to work in IIT@CBN as a support Technician for the Multifunctional Neural Interfaces with Deep Brain Areas research line where she manages and performs activities and experiments related to the in vivo testing of newly developd optoelectronic devices, partecipating also in their design and fabrication. Additionally, she is responsible for the draw up of the animal use protocols, required in research activities/projects involving vertebrate animals.



All Publications
2022
Bianco M., Pisanello M., Balena A., Montinaro M., Pisano F., Spagnolo B., Sabatini B. L., Pisanello F., De Vittorio M.
Extending the capabilities of depth-resolved fiber photometry in brain tissue with tapered optical fibers
Optogen
Poster Conference
2022
Spagnolo B., Balena A., Peixoto R. T., Pisanello M., Sileo L., Bianco M., Rizzo A., Pisano F., Qualtieri A., Lofrumento D., De Nuccio F., Assad J., Sabatini B. L., De Vittorio M., Pisanello F.
Fibertrodes: achieving brain optical control with single and multi-channel artefact-free implantable neural probes
7th International Workshop on Technologies for Optogenetics and Neurophotonics - OPTOGEN2022
Poster Conference
2022
Montinaro C., Pisanello M., Bianco M., Spagnolo B., Pisano F., Balena A., De Nuccio F., Lofrumento D. D., Verri T., De Vittorio M., Pisanello F.
Influence of brain anatomy on functional fluorescence collection from brain tissue
OSA Biophotonics Congress
Poster Conference
2022
Montinaro C., Pisanello M., Bianco M., Spagnolo B., Pisano F., Balena A., De Nuccio F., Lofrumento D.D., Verri T., De Vittorio M., Pisanello F.
Influence of brain anatomy on functional fluorescence collection from brain tissue
Optics InfoBase Conference Papers
Conference Paper Conference
2022
Montinaro C., Pisanello M., Bianco M., Spagnolo B., Pisano F., Balena A., De Nuccio F., Lofrumento D. D., Verri T., De Vittorio M., Pisanello F.
Influence of local brain anatomy on the spatial extent of fiber photometry signal
FENS Forum 2022
Poster Conference
Scientific Talks
2022
Pisanello F., Pisano F., Pisanello M., Spagnolo B., Sileo L., Balena A., Bianco M., Maglie E., Zheng D., Collard L., Montinaro C., Lee S.J., Lee J., Peixoto R., De Angelis F., Tantussi F., Valiente M., De La Prida L., Mandelbaum G., Sabatini B. L., De Vittorio M.
MULTIFUNCTIONAL OPTICAL NEURAL INTERFACES WITH TAPERED OPTICAL FIBERS
BIOEL International Winterschool on Bioelectronics - 12-19 March 2022 - Kirchberg in Tirol, Austria
School (Summer school, ...)
2022
Pisanello F., Pisano F., Spagnolo B., Zheng D., Collard L., Bianco M., Balena A., Kashif F. M., Andriani S., De Vittorio M.
NEUROPHOTONICS WITH TAPERED OPTICAL FIBERS: FROM DEPTH-RESOLVED FIBER PHOTOMETRY TO IMPLANTABLE NANOPLASMONICS
Complex Media NeuroPhotonics workshop, October 24-27 2022, Brno
Workshop/Symposium
2022
Pisanello F., Pisano F., Spagnolo B., Pisanello M., Balena A., Sileo L., Peixoto R., Al-masmudi M., Kashif M. F., Cid E., Parras T. J., Sanchez-Aguilera A., Grande M., Valiente M., De La Prida L., Sabatini B., De Vittorio M.
Tapered optical fibers technology: sensing functional fluorecsence, 3d electrical signals and Raman scattering in deep brain regions
Harvard Armenise Symposium 2022
Workshop/Symposium
2022
Pisanello F., Pisano F., Spagnolo B., Pisanello M., Balena A., Sileo L., Peixoto R., Al-masmudi M., Kashif M. F., Cid E., Parras T. J., Sanchez-Aguilera A., Grande M., Valiente M., De La Prida L., Sabatini B., De Vittorio M.
The Nanobright EU project
BIOCUBE 2022, Sestriere (TO) 15 Dec 2022
Workshop/Symposium
2021
Pisanello F., Pisano F., Spagnolo B., Pisanello M., Balena A., Sileo L., Peixoto R., Al-Masmudi M., Kashif M.F., Sanchez-Aguilera A., Grande M., Tantussi F., De Angelis F., Valiente M., de la Prida L.M., Assad J., Sabatini B., De Vittorio M.
MULTIFUNCTIONAL NEURAL INTERFACES WITH TAPERED OPTICAL FIBERS
International Meet & Expo on Laser, Optics and Photonics (OPTICSMEET2021)
Conference
Oral presentations
2021
Spagnolo B., Peixoto Rui T., Sileo L., Pisanello M., Pisano F., Assad J.A., Sabatini B.L., De Vittorio M., Pisanello F.
Fibertrodes: a FIB based fabrication approach for interfacing brain activity with negligible photoelectric noise
MNE 2021
Conference
2021
Spagnolo B., Balena A., Peixoto Rui T., Sileo L., Pisanello M., Pisano F., Assad J.A., Sabatini B.L., De Vittorio M., Pisanello F.
Fibertrodes: a FIB based fabrication approach for interfacing brain activity with negligible photoelectric noise
MNE
Conference
2021
Spagnolo B., Sileo L., Pisanello M., Pisano F., Balena A., DeVittorio M., Pisanello F.
Interfacing with small brain volumes taperedfiber-based optrode
OSA: Biophotonics Congress
Conference
2021
Spagnolo B., Peixoto R.T., Sileo L., Pisanello M., Pisano F., Assad J.A., Sabatini B.L., DeVittorio M., Pisanello F.
Interfacing with small brain volumes with tapered fiber-based optrode
Optics InfoBase Conference Papers
Conference
2020
Spagnolo B., Pisanello M., Sileo L., Pisano F., Balena A., Pisanello F., DeVittorio M.
Advanced optoelectronic devices for neuroscience
ICTON 2020
Conference