Micro and nano technologies for studying cancer cells
Cancer cell motility is one of the major events involved in the metastatic process. Tumor cells that disseminate from a primary tumor can migrate into the vascular system and, being carried by the bloodstream, transmigrate across the endothelium, giving rise to a new tumor site. We develop technologies and methods to better understand cell dynamics underlying tumor invasiveness. In particular, we exploit two-photon lithography in its full potential to create innovative 3D porous structures, e.g. by modulating pore size and materials mechanical properties, which allow to study cell/structure interactions and realize cell sorting tools on the base of their different invasive behaviour.
- Scientific Reports 2015 https://www.nature.com/articles/srep10531
- IEEE Nano 2017 http://ieeexplore.ieee.org/document/7737036/